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References Asano, Y

Anyone with copper-metabolism disorders, active malignancy, or during pregnancy/breastfeeding should avoid it, and everyone should consult a licensed clinician first

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Nevertheless, all three receptors are combined in one family because the amphibian 14-mer peptide homolog Bn (Sequence: Pyr-QRLGNQWAVGHLM-NH 2 ), which was isolated from the skin of the European fire-bellied toad, binds and activates all three receptors (Anastasi et al., 1972)