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Oxaliplatin downregulates expression of potassium channel Kv2.2 in the somatosensory cortex, thereby requiring a smaller stimulus for neuronal firing (Thibault et al., 2012)

L-Carnosine has traditionally been used as an oral supplement for systemic benefits including exercise performance enhancement, neuroprotection, and general antioxidant support

1a, 2g, h), while the side chain points into the core of the receptor and is surrounded by hydrophobic amino acids, namely C130 3.32 , L133 3.35 , I185 4.61 , L197 5.34 , F261 6.51 , and L288 7.39