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What they found: Dose-dependent stimulation of type II collagen (up to 2.5 baseline at 100 nM) Stimulation of aggrecan (up to 1.8 baseline) Inhibition of MMP-13 by ~40 % Partial protection against IL-1-induced matrix degradation Why it matters: It opened a completely new research area for AOD-9604 beyond lipolysis

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It is synthesized by microorganisms in cows and sheep

Lipolytic fragment Research and Clinical Studies Fragment 176-191 and Fat Cells As mentioned, Fragment 176-191 is believed to potentially increase fat burning through different mechanisms, which may include the upregulation of the beta-3 adrenergic receptors