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Besides chronic liver diseases, XCHD is also widely used in clinical practice for its regulatory effects on common mental disorders such as depression (Sun et al., 2023)

Besides, TP treatment might disrupt immune homeostasis and induce liver hypersensitivity through the regulation of NF-B-dependent pro-survival genes (Yuan et al., 2020)

Overall, these findings highlight the promising yet preliminary nature of BPC-157 and TB-500 research and reinforce the urgent need for standardized, large-scale clinical trials and robust safety monitoring frameworks before these compounds can be confidently integrated into clinical practice

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