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10.1016/j.jconrel.2022.05.063 204 TangY.LiY.YuH.GaoC.LiuL.XingM.et al (2014)

G339C and p.L348fs, which are observed in ~50% of GSD1b patients

p53 p53 is one of the most well-studied tumor suppressor, and is activated in response to various stressors including DNA damage, telomere attrition, mitochondrial, oxidative or oncogenic stress