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The induction of sperm shape-abnormalities in mice and humans.Chemical Mutagens, 1978

doi: 10.1016/j.cell.2022.08.005 209 WingJBTanakaASakaguchiS

It is proposed to work by binding GHRH receptors on pituitary somatotroph cells, prompting the pituitary to synthesize and release its own growth hormone in a pulsatile pattern, with the body's somatostatin feedback loop still intact so the effect is self-limiting rather than a constant hormone flood