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Firstly, most existing studies focus on animal and cellular experiments and lack large-scale clinical trials

C.PereiraS

Talanta 58(1):7796

Moreover, the levels of vitamin C and paraoxonase 1 (PON1) activity were markedly lower in individuals with MDD than in control individuals [126]

Here, we attempted to untangle this matter adopting a dual approach based on NMR-based metabolomics and UPLC/MS analysis to dissect the serum metabolomic pathways dysregulations in a cohort of PD patients characterized with motor, cognitive, dopaminergic treatment and nutritional assessments