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In this study, we tested the hypothesis that CHAC1 inhibition may preserve the intracellular glutathione in skeletal muscles and thus represent a novel strategy to treat muscle wasting in cachexia conditions

Approximately 100 mg of tissue was then transferred to a 1.5-mL Eppendorf tube, followed by homogenization on ice using an electrical disperser (T 10 basic ULTRA-TURRAX 558 from IKA, equipped with an S10N-5G Dispersing Element) in 1 mL of 2 Sample Buffer (100 mM Tris-HCl, pH 6.8, 4% (m/v) SDS, 20% (v/v) glycerol, and 4% (v/v

An inflammatory, autoimmune demyelinating disease of the central nervous system in rodents that has high pathological and clinical similarities to human multiple sclerosis and is the most used experimental model for the disease

Non-occlusive mesenteric ischemia (NOMI), in disparity, does not include a physical occlusion of the mesenteric arteries