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Epigenetic reprogramming using 5-azacytidine promotes an anti-cancer response in pancreatic adenocarcinoma cells

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More recently, an in vitro investigation by Kim SY revealed that lyso-Gb3 can raise ROS levels via a receptor-interacting protein kinase-3 (RIPK3)-dependent pathway, leading to mitochondrial dysfunction by inhibiting respiratory chain complexes I and III (81)