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Compared to healthy mice, DSS treatment caused a 12-fold increase in Il1b, a 29-fold increase in Il6, a three-fold rise in Tnf, and a six-fold rise in Nos2 mRNA levels

This receptor binding increases intracellular cAMP and activates neuropeptide pathways, promoting satiety that leads to lower caloric intake in animal feeding studies

Trends Biotechnol 21 , 210-6 (2003) CrossRef PubMed Google Scholar 102.Hussein G, Goto H, Oda S, Sankawa U, Matsumoto K, Watanabe H, Antihypertensive potential and mechanism of action of astaxanthin: