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When the FRET is terminated (by separating donor and acceptor), an increase of donor fluorescence can be detected

Certain medications, including antacids containing aluminium, bile acid sequestrants (e.g., cholestyramine), and some lipid-lowering drugs, may reduce the absorption of UDCA

eClinicalMedicine 73 , 102655 (2024)

The cellular redox state modulates SIRT1 activity, enabling antioxidants to act by key pathways ( SIRT1/FOXOs , SIRT1/NF-B , and SIRT1/p66Shc ) to protect CVD Further complexity arises from the regulatory crosstalk involving transcription factors (TFs) such as NF-B and sirtuins

When collagen levels drop, the structural integrity of the skin weakens