glutathione and dystonia Purine Metabolism Dystonia: Perspectives of a Long‐Promised Relationship - Sorrentino - 2025 - Annals of Neurology The glyoxylase system comprises two

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Chromatin structure and gene accessibility to transcriptional machinery are regulated by modifications to both DNA and histone tails (Handy et al., 2011

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described the induction of arginine hypomethylation of FUS using adenosine-2,3-dialdehyde, an extensively used inhibitor of arginine methyltransferase activity

Consistent with the observed reduced CNV lesion growth in VEGFA hyper /Casp1 / /Casp11 / mice compared to VEGFA hyper mice, we observed that pharmacologic inhibition of caspase1 significantly reduced laserinduced CNV lesion growth when compared to DMSOtreated control mice (Fig 8F)