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[2] Broader reviews position the peptide as producing an angiogenic, healing-promoting effect across gastrointestinal and extra-gastrointestinal tissues, tying its action to the nitric-oxide system and to standard angiogenic growth factors

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Endogenous cannabinoid release within prefrontal-limbic pathways affects memory consolidation of emotional training

The most commonly reported effects are mild and transient: slight redness at the injection site, occasional mild fatigue in the first few days of a protocol reflecting the circadian recalibration effect, and in some patients a temporary increase in dream vividness associated with improved REM architecture

Emotional Stability: Thought to modulate GABAergic pathways involved in anxiety and stress responses