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Research has shown that p53 can suppress the expression of SLC7A11, a key component of the cystine/glutamate antiporter (X c system), leading to the inhibition of cystine uptake and sensitization to ferroptosis

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& Epperson, C

This system-level integrated strategy provides insight into how SalA restores behaviour and molecular homeostasis throughout aging, revealing understanding of conserved mechanisms of neurodegenerative decline resilience