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Providing support for a causal link between a negative energy state and increased Parasutterella abundance, a rat model of obesity, which showed similar Parasutterella relative abundances in animals maintained on HFD and those maintained on normal chow but exhibited a treatment-induced increase in Parasutterella relative abundance, displayed a negative correlation between Parasutterella and body weight 82

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Rather, hypochloremia can promote sodium retention in several ways: Hypochloremia appears to stimulate renin secretion, thereby activating the renin/angiogensin/aldosterone axis

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