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645 Transcriptome sequencing of neuropathic pain mice showed that TRIM28 is a crucial regulator of ferroptosis, and TRIM28 regulates iron homeostasis and ferroptosis in spinal microglia by downregulating GSK3 expression and regulating autophagy

MTHFR = 5,10-methylene-THF reductase

SNPs are primarily located in the non-coding region of the GPX3 gene and exhibit a positive association with the susceptibility to cancer development (43)