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High-dose folic acid supplementation alters the human sperm methylome and is influenced by the MTHFR C677T polymorphism

While this doesn't always lead to symptoms, it may explain why some patients feel different after starting the medication

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On the other hand, it is worth remembering that this mean effect size was achieved following the implementation (in the original studies) of all the methodological procedures and restrictions described in the previous two sections, each of which are designed to facilitate the detection of effects

Medullary thyroid carcinoma