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Hence, these collected results established the substantial stability of the docked flavonoids with mh-Tyr and to function as an alternative substrate in presence of a specific substrate to reduce or inhibit the catalytic activity of the mh-Tyr enzyme, as predicted from docked poses (Fig

Interestingly, the metabolomics results showed that the synergistic effect was related to metabolic disorders, especially the substantial influence on glycerophospholipid metabolism, which significantly increased membrane permeability

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Kri S, Szab C, Kelemen O

This widespread dietary exposure is concerning, as ACR has been linked to cytotoxicity (Kianfar et al., 2020), neuroinflammation (Yazadanpanah et al., 2023), and carcinogenicity (Koszucka et al., 2020)