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This concern may have originated from a 1959 study that first raised the possibility of diuretics affecting glucose metabolism (Freis and Finnerty, 1959) based on the effects of hydrochlorothiazide

Shoot length increased under each treatment (58.8 %, 47.1 % and 47 %), as did root length (56.0 %, 40.0 % and 38 %), along with fresh weight (58.8 %, 29.4 % and 41.2 %) and dry weight (57.1 %, 47.6 % and 52.4 %) when compared to non-treated controls

2013), resulting in the activation of GSK3

Three genes expressed in relation to lipid metabolism considered as potential biomarkers for the diagnosis and treatment of diabetic peripheral neuropathy

The author gratefully acknowledges support from the National Agency for Research and Development of the Republic of Moldova through grant number 25.80013.5007.07RE