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Moreover, the mechanism by which IGF-1 promotes the production of NK cell populations is also associated with upregulated mRNA signals for NFIL3 ( E4BP4 ) and ID2 , which are critical transcription factors for NK cell development 33,42

We turn now to those mechanisms for phenotypic variation that are demonstrably dependent on environmental cues

Geraci MJ , McCoy SL , Aquino ME

We constructed standardized experimental models encompassing murine full-thickness burn injuries [13], rat dermal incisional wounds [13], and rodent skeletal muscle contusion models (Figure S1)