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Specifically, the higher-order SNCA aggregates play a role in microglial activation and astrogliosis (Chavarra et al., 2022), which is mediated through several receptors

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Kraus P, Deyhle M, Maier KH, Roller E, Wei HD, Cldon P

(PubMed) That distinction matters, because it means that even if a compound influences telomerase or telomere dynamics in cells, that does not automatically mean it will extend human lifespan in a clinically meaningful way

Takeaway: Use NAC when you need to boost glutathione naturally , support lungs and brain , or help with liver detox recovery