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Yoshida, et al

Sinularin exhibited higher antioxidant properties than dihydrosinularin

Post-transplant relapse is often driven by the downregulation of host miHAs and the functional exhaustion of miHA-specific CD8 T-cells characterized by the upregulation of inhibitory markers like PD-1 and Tim-3, which ultimately leads to GvL resistance (103105)

Figure 1 Furthermore, SAM serves as a methyl donor, methylating DNA and proteins, including histones (Zade et al., 2023), which in turn influences epigenetic regulation, and gene expression ( Figure 1 )