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Psychiatry 137 ZhangY.MaoZ.PanL.LingZ.LiuX.ZhangJ.et al (2018)

diet and lifestyle factors are also important

A recent study showed that use of a partly humanized anti-HMGB1 monoclonal antibody in mice resulted in a 50% reduction in liver injury after APAP overdose, with prolonged therapeutic efficacy when compared to NAC [161]