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The body has had 12+ weeks to adapt to amylin signaling

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Figure 4 These three cases show how exposure to different types of toxic metals (elemental mercury, organic mercury, and silver) can result in some overlap in their distribution in the brain (e.g., all present in the locus ceruleus), but that different regions and cells of the brain can be affected (e.g., either grey or white matter oligodendrocytes)