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Description

No organ toxicity, mutagenicity, or teratogenic effects were observed

Cystine depletion can induce ferroptosis

Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus

During this process, the nerve sends chemical signals and nutrients to the site of the injury

These variable results both in experimental studies and in humans make it difficult to decide which models and experimental conditions are most relevant for the human pathophysiology in the context of steatosis and APAP hepatotoxicity