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This review is the first to systematically characterize HDI molecular mechanisms at both pharmacodynamic (PD) and pharmacokinetic (PK) levels, elucidating how herbal medicines modulate ACDs efficacy and safety through antagonism/synergy/detoxification target, metabolic enzymes, and transporters

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Today, many functional medicine practitioners incorporate these herbs into detox protocols, often alongside supportive nutrients like N-acetylcysteine (NAC), curcumin, and alpha-lipoic acid

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Shadman M, Gauthier J, Hay KA, Voutsinas JM, Milano F, Li A, et al

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