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2024 Oct 18;143(Pt 2):113427

Murrough, James W

The research discovered MPTP was metabolized by astrocytes in the brain to 1-methly-4-phenylpyridium (MPP+) which had a distinctively similar composition to a popular pesticide

The applicant further stated that in clinical trials, SPEVIGO was associated with clinically significant improvements in patient-reported psoriasis symptoms, including fatigue, and significant decreases in markers of systemic inflammation