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NPY treatment partially reversed this inhibition and increased the activities of SOD and GSH-Px (Fig

Lapenna D., Glutathione and Glutathionedependent Enzymes: From Biochemistry to Gerontology and Successful Aging, Ageing Research Reviews 92 (2023): 102066

Moreover, BH4 plays a pivotal role in antioxidant defense and the removal of nitrogen oxides (80)

and Valado, A

Subsequent studies will need to clearly evaluate the safety and risk associated with more invasive measures that efficiently transduce or treat smaller areas, compared with broader, less-invasive means of distribution associated with limited brain penetrance due to the need to bypass the BBB