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Furthermore, a significant aggravation of LIR-mediated damage has been documented in a second study performed in iNOS knockout mice (548), although the relevance of these findings is questionable, given the absence of iNOS expression in wild-type control mice in this particular study

Serious side effects are rare but can occur

Louapre C, Rosenzwajg M, Golse M, Roux A, Pitoiset F, Adda L, et al