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In a more recent multicenter, randomized, double-blind, placebo-controlled study, supplemental vitamin E (2,000 IU/day

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Abbreviations AMPK: AMP-activated protein kinase COX II: Cytochrome c oxidase subunit II mtDNA: Mitochondrial DNA NEFA: Nonesterified fatty acid PCR: Polymerase chain reaction PGC-1: Peroxisome proliferator-activated receptor- coactivator-1 RPE: Rating of perceived exertion VAS: visual analogue scale References Meister A