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Diagnostic methods such as GC/MS became more widely available in the 1980s and later so that the patients with IEMs were diagnosed with an IEM instead of Reyes syndrome

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169 ToyofukuT.OkamotoY.IshikawaT.SasawatariS.KumanogohA

doi: 10.1001/jama.2013.282834

Moreover, as shown in Table 3, PDEVs display a distinct translational profile when compared with mammalian EVs and synthetic liposomes