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However, cranial magnetic resonance imaging showed a wide range of long T1 and T2 signals in the bilateral frontotemporal parietal lobes, short T1 signals in the bilateral pallidum (Figure 2)

You can think of them like tools in a toolbox or apps on your phone, each designed to help the body do a job better

In normal individuals, a severe deficiency of thiamine (VitaminB1)will produce beriberi, a disease of diffuse symptoms associated with decreased activity of the 3 thiamine-dependent enzymes (pyruvate dehydrogenase, -ketoglutarate dehydrogenase, and transketolase)

Souffreau J