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Dose modification may be needed if you experience: Elevated IGF-1 levels Blood sugar changes or insulin resistance Fluid retention or joint pain Routine lab testing, including IGF-1, fasting glucose, HbA1c, and lipid profiles, ensures safety and effectiveness

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Moreover, the significant therapeutic potential of gene interventions targeting the p53- FOXO3 regulation of cartilage degeneration at the cartilage level and abnormal remodeling in the subchondral bone during obesity-induced degeneration were elucidated