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59 The mechanisms of action of clinically used ASOs mainly include ribonuclease H (RNase H)-mediated degradation (Fig

The acute hypotensive response activates the baroreceptor reflex, producing compensatory reflex tachycardia characterized by shortened RR intervals on ECG

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No need to worry: its the Jarisch Herxheimer reaction and is simply a sign that you are detoxing

This means that both surgery and non-surgical management have been shown to lead to similar functional outcomes, so youll have to weigh the potential benefits and risks to determine which option is most appropriate for you and your goals