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Signs of infection are increasing redness, swelling, pain, and fever

The nasal route has the advantage of self-medication by patients due to the easy accessibility of the nasal cavity ( via nasal routes for systemic effects (Ozsoy et al., 2009)

(see Table 24) Table 24

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Eur J Pharmacol 570:212221 Sebecic B, Nikolic V, Sikiric P, Seiwerth S, Sosa T, Patrlj L et al (1999) Osteogenic effect of a gastric pentadecapeptide, BPC-157, on the healing of segmental bone defect in rabbits: a comparison with bone marrow and autologous cortical bone implantation