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In a similar analysis, in participants 56 years of age and older (Pfizer-BioNTech COVID-19 Vaccine = 7,960, placebo = 7,934), serious adverse events were reported by 0.8% of Pfizer-BioNTech COVID-19 Vaccine recipients and by 0.6% of placebo recipients who received at least 1 dose of Pfizer-BioNTech COVID-19 Vaccine or placebo, respectively

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ScienceDirect / Journal of Injection Technique Studies

This contributes to widespread breakthrough infections (BTIs), defined as infections 2 weeks post-vaccination, which may have affected 40-45% of vaccinated cohorts since 2021