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The palmitoyl group increases its logP value (lipophilicity), allowing better diffusion through the stratum corneum compared to unmodified GHK (logP 2000 mg/kg) or irritation reported in patch tests, as per Cosmetic Ingredient Review assessments

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This therapy may have the potential to escape decompensated cirrhosis, resulting in avoiding liver transplantation

Brady M, Janovitz E

Elevated systolic or diastolic pressure causes increased cardiovascular risk, and the absolute risk increase per mmHg is greater at higher blood pressures, so that even modest reductions of severe hypertension can provide substantial benefit