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However, the synthesis pathways of flavonoids are relatively numerous and complex, so we have briefly summarized a flowchart for a better understanding of flavonoid biosynthesis pathways ( Figure 7 )

All metabolites seem to be cytotoxic to the renal tubular epithelium, causing the destruction of intracellular organelles, although glycolate is thought to be the main contributor to the life-threatening nephrotoxic effects

Acknowledgments/Funding: The authors would like to thank Drs

Golgi-LaccID did not show labeling with BP in living cells (Supplementary Fig

Individuals vary in how quickly their bodies can metabolize alcohol