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The coordinated actions of these mechanisms ensure proper distribution of copper ions in the body while preventing harmful effects such as hydroxyl free radical formation from free copper ions, thus protecting cells from damage

Kato T, Stine OC, McMahon FJ, Crowe RR

Adaptive randomized study of idarubicin and cytarabine alone or with interleukin-11 as induction therapy in patients aged 50 or above with acute myeloid leukemia or high-risk myelodysplastic syndromes