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Peripheral nerve damage involves ischemia, Schwann cell dysfunction and axonal degeneration, particularly affecting unmyelinated C fibres organized in Remak bundles, ultimately leading to demyelination in more severe cases

Bulking agents (microcrystalline cellulose, dicalcium phosphate), L-carnitine free form (500mg), anti-caking agents (silicon dioxide, vegetable stearic acid, vegetable magnesium stearate), crosslinked cellulose gum, glazing agents (hydroxypropylmethyl cellulose, vegetable glycerin made from palm kernel oil and coconut oil, carnauba wax) As a food supplement for adults, one (1) tablet daily, with juice or water in between meals, or as directed by a healthcare practitioner

Orthodontic treatment pain or ulceration is another area where a curcumin gel might soothe the mouth ulcers that sometimes occur with braces (Srivastava et al., 2018)

J Hum Hypertens 1999;13:203-8

Gholamhoseinian et al