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More studies are needed to understand the impact of these changes

To study the mechanisms involved in SHBG regulation by resveratrol, we initially analyzed two key transcription factors known to control hepatic SHBG expression, namely HNF-4 and PPAR 8,9 , but their levels did not change in resveratrol-treated HepG2 cells

doi: 10.1126/science.aaa3872 104 GuanX

Infect Agent Cancer 18:7 Groven N, Reitan SK, Fors EA, Guzey IC (2021) Kynurenine metabolites and ratios differ between chronic fatigue syndrome, fibromyalgia, and healthy controls