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What should be monitored over time

Redox regulation: mechanisms, biology and therapeutic targets in diseases

Macrophage polarization and renal fibrosis Fibrosis is the pathophysiological alteration of the kidneys in response to endogenous or/and exogenous stimuli, leading to a marked reduction in glomerular filtration rate and deterioration of renal function ( It is well known that inflammation plays an important role in renal fibrosis ( Renal fibrosis is characterized by three phases: the first phase of inflammation, the second phase of fibrosis mediated by fibroblasts and collagen production, and the final phase of scar formation

They are produced from the yolk sac and become permanently resident in the neural tissues taking on a traditional inflammatory-prone M1 phenotypic expression or the tissue repair M2 phenotypic expression (Daneman and Prat, 2015

This simple method was shown to be reproducible and effective