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When delivered as a boost to previous BCG vaccination, the combination of these vectors conferred significant protection in mice, compared to BCG alone ( To accelerate TB vaccine development, we employed a mass spectrometry-based immunopeptidomics approach to identify novel mycobacterial antigens

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This study supported the approval of a third dose of vaccine for immunocompromised patients

However, because of side effects or decreased effectiveness over time, only about 3040% remain well-controlled by medications alone in the long term

Key Differences at a Glance Pathway & Mechanism Comparison Understanding their distinct biological pathways is the key to this comparison