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Because herbal treatments frequently incorporate holistic interventions like dietary guidance, lifestyle modification, and counselling in addition to medication, designing strong randomized clinical trials (RCTs) is difficult because of blinding issues (Gautama 2021)

doi: 10.3389/fcell.2021.739413

Similarly, massage of the affected regions of the leg may provide counter stimuli that can alleviate RLS symptoms (Gamaldo 2006)

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Amyotrophic lateral sclerosis (ALS): GSH deficiency is observed in ALS patients, potentially accelerating nerve cell death