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Is metformin poised for a second career as an antimicrobial

Zhu Y, Shao Y, Qu X, Guo J, Yang J, Zhou Z

However, parameters had different intensities of effects

However, in NDDs, chronic or overwhelming ER stress shifts the UPR toward maladaptive responses, contributing to neuronal dysfunction and death, e.g., Prolonged PERK activation has been implicated in AD, PD, and ALS, where it contributes to chronic ER stress and neuronal death