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10.1074/jbc.M501485200 54

Khaled K, Abu-Amero, Morales J, et al

doi: 10.1038/sj.emboj.7601575 34 DeyN.RoyU

Defects in either transsulfuration and remethylation will lead to disruptions in the metabolism of homocysteine and elevated plasma levels of homocysteine.9 Enzyme Deficiencies and Hyperhomocysteinemia The transsulfuration and remethylation pathways rely on the activity of enzymes to function properly