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qtot -0.636 5 OG311 1 ful O5 5 -0.636 15.9994

Pharmaceutically acceptable carriers and diluents are well known in the art (see, e.g., Remington, The Science and Practice of Pharmacy (21 st Edition, Lippincott Williams and Wilkins, Philadelphia, PA.) and The National Formulary (American Pharmaceutical Association, Washington, D.C.)) and include sugars (e.g., lactose, sucrose, mannitol, and sorbitol), starches, cellulose preparations, calcium phosphates (e.g., dicalcium phosphate, tricalcium phosphate and calcium hydrogen phosphate), sodium citrate, water, aqueous solutions (e.g., saline, sodium chloride injection, Ringer's injection, dextrose injection, dextrose and sodium chloride injection, lactated Ringer's injection), alcohols (e.g., ethyl alcohol, propyl alcohol, and benzyl alcohol), polyols (e.g., glycerol, propylene glycol, and compositions of the disclosure must be acceptable in the sense of being compatible with the other ingredients of the formulation and not injurious to the subject

Nrf2 can protect cells from damage caused by lipid peroxidation products such as 4-hydroxynonenal and acrolein, thereby inhibiting iron-dependent cell death

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