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Experimental studies further show that bitter melon alters key carbohydrate-metabolizing enzymes and promotes pancreatic -cell regeneration (28), while both animal and clinical trials demonstrate its ability to lower fasting blood glucose and HbA1c levels

2.3.6 Flavonoids Flavonoids, a significant class of polyphenolic secondary metabolites derived from plants, possess antioxidant properties that can help prevent cardiovascular diseases and chronic illnesses [88, 91]