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[Para 1 85] Cells were allowed to grow for seven days at which time the experiment was terminated and the cytoproliferation assay was run

However, only 8% of glioma patients respond effectively to immunotherapy, despite its promising results in many other tumors, which is predominantly attributed to the unique tumor immunosuppressive microenvironment in gliomas

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7 Conclusions and future perspectives Plant roots are essential for plant growth, stress perception, and environmental adaptation, and accumulating evidence establishes melatonin as a key integrative regulator of root system architecture (Shi et al., 2015)