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Co-expression module detection used a dynamic tree cut algorithm limited to a minimum module size of 30 genes and a cut height of 0.25 for module merging

Human samples obtained from the Massachusetts General Hospital ADRC funded by P30AG062421 and the Columbia ADRC funded by P30AG066462, R01AG072474 and U24AG056270

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Accordingly, in a mouse amnesia model induced by scopolamine, ISA can decrease the damages of the cornu ammonis regions of mouse hippocampus (which is critical in memory and cognition) and alleviate the cognitive impairment, as revealed by Y-maze, passive avoidance and water maze tests